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Beschreibung

Dolcontin (Morphine Sulfate) – Extended-Release Opioid Analgesic (Rx, Controlled)

Dolcontin (morphine sulfate) is a strong opioid analgesic used for the management of severe chronic pain that requires continuous, around-the-clock opioid treatment. It is commonly used in cancer pain, advanced chronic pain conditions, and palliative care.

Morphine is a full μ-opioid receptor agonist, acting in the central nervous system to alter pain perception and response, producing strong analgesia. The extended-release formulation provides long-lasting pain control with stable plasma levels, reducing the need for frequent dosing.

Wichtige Details

  • Active Ingredient: Morphine sulfate
  • Drug Class: Strong opioid analgesic
  • Indikationen
    • Severe chronic pain
    • Cancer-related pain
    • Palliative care pain management
  • Mechanism of Action: μ-opioid receptor activation → central pain inhibition
  • Formulation Type: Extended-release (prolonged action)
  • Verschreibungsstatus: Streng verschreibungspflichtiges Arzneimittel

Spezifikationen

  • Dosage Forms: Extended-release tablets
  • Common Strengths: 10 mg, 30 mg, 60 mg, 100 mg (varies by region)
  • Verwaltung: Oral
  • Onset of Action: Gradual (within 1–2 hours)
  • Duration of Action: ~8–12 hours
  • Half-Life: ~2–4 hours (active metabolites prolong effect)
  • Metabolism: Hepatic (glucuronidation)
  • Ausscheidung: Renal
  • Lagerung: Raumtemperatur

Dosierung & Verabreichung

  • Dose is individualized based on pain severity and prior opioid use
  • Typically taken every 12 hours (twice daily)
  • Tablets must be swallowed whole (do not crush or chew)
  • Requires careful titration and medical supervision
  • Not suitable for immediate or breakthrough pain relief

Kompatibilität / Geeignete Verwendung

  • Patients with severe chronic or cancer-related pain
  • Individuals requiring continuous opioid analgesia
  • Palliative care settings
  • Must be managed under specialist supervisionContraindications
  • Severe respiratory depression
  • Acute or severe asthma (unmonitored setting)
  • Paralytic ileus
  • Known hypersensitivity to morphine
  • Acute intoxication with alcohol or CNS depressants

Why Choose Dolcontin?

Dolcontin provides long-acting morphine-based pain control, making it suitable for patients requiring stable, continuous relief from severe chronic pain. It is a cornerstone therapy in specialist pain management and palliative care, but must be used under strict medical supervision due to its potency and risk profile.

 

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