Descripción

Stilnoct (Zolpidem Tartrate) – Sedative-Hypnotic for Short-Term Insomnia (Rx, Controlled)

Stilnoct (zolpidem tartrate) is a non-benzodiazepine sedative-hypnotic used for the short-term treatment of insomnia, particularly for difficulty falling asleep.

It works by selectively binding to the GABA-A receptor complex (omega-1 subtype), enhancing inhibitory neurotransmission in the brain. This produces sedation, reduced sleep latency, and improved sleep onset, without being a classical benzodiazepine.

Because of its rapid onset and short duration, it is typically used for sleep initiation insomnia rather than long-term sleep disorders.

Key Details

• Active Ingredient: Zolpidem tartrate
• Drug Class: Non-benzodiazepine hypnotic (Z-drug)
• Indication: Short-term insomnia treatment
• Mechanism of Action: GABA-A receptor modulation → CNS sedation
• Prescription Status: Controlled prescription medicine

Especificaciones

• Dosage Forms: Oral tablets
• Common Strengths: 5 mg, 10 mg
• Administration: Oral, immediately before bedtime
• Onset of Action: ~15–30 minutes
• Duration of Action: ~6–8 hours
• Half-Life: ~2–3 hours
• Metabolism: Hepatic (CYP3A4)
• Excretion: Renal
• Storage: Room temperature

Dosage & Administration

• Typical dose: 5–10 mg once nightly
• Must be taken only when full sleep time (7–8 hours) is available
• Should be used for the shortest possible duration
• Dose adjustments may be required for elderly or sensitive patients
• Do not take with or immediately after a heavy meal (delays onset)

Compatibility / Suitable Use

• Patients with short-term insomnia or sleep-onset difficulty
• Individuals experiencing temporary sleep disruption (stress, travel, schedule changes)
• Not intended for long-term chronic insomnia treatment
• Requires medical supervision

Contraindicaciones

• Severe respiratory insufficiency
• Sleep apnea syndrome
• Severe hepatic impairment
• Known hypersensitivity to zolpidem
• History of complex sleep behaviors with zolpidem

Why Choose Stilnoct?

Stilnoct (zolpidem) is a fast-acting sleep medication designed to help patients fall asleep quickly and improve sleep onset in short-term insomnia. It is effective when used correctly but must be limited to short durations due to dependence and safety risks.