Beskrivning
Veklury – Antiviral Treatment for COVID-19 (Rx)
Veklury (remdesivir) is an antiviral medication used for the treatment of COVID-19 caused by SARS-CoV-2 in hospitalized patients and certain non-hospitalized high-risk patients. It is a nucleotide analog prodrug that inhibits viral replication by targeting the RNA-dependent RNA polymerase enzyme, which is essential for viral RNA synthesis.
By blocking viral replication early in the infection cycle, remdesivir can help reduce disease progression and improve recovery time in appropriate patients.
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Key Details
- Active Ingredient: Remdesivir
- Brand Name: Veklury
- Drug Class: Antiviral (RNA polymerase inhibitor)
- Indication: Treatment of COVID-19
- Mechanism of Action: Inhibits viral RNA-dependent RNA polymerase → stops viral replication
- Use Setting: Hospital or supervised outpatient infusion
- Prescription Status: Prescription-only medicine
Specifikationer
- Dosage Form: Powder for concentrate for solution for infusion / IV solution
- Route of Administration: Intravenous (IV) infusion only
- Typical Treatment Duration: 3 to 5 days (depending on severity and setting)
- Loading Dose: 200 mg IV on day 1
- Maintenance Dose: 100 mg IV once daily thereafter
- Infusion Time: ~30–120 minutes (per protocol)
- Metabolism: Rapid intracellular conversion to active metabolite
- Excretion: Primarily renal and fecal pathways
- Storage: Refrigerated or controlled room temperature depending on formulation
Dosage & Administration
- Administered in clinical or supervised healthcare settings
- Requires IV infusion by trained healthcare professionals
- Dose adjustments may be required in patients with renal or hepatic impairment
- Treatment is most effective when started early in infection
Compatibility / Suitable Use
- Hospitalized patients with moderate to severe COVID-19
- Non-hospitalized high-risk patients (in specific protocols)
- Patients requiring oxygen support or at risk of progression
- Must be used under strict medical supervision
Why Choose Veklury?
Veklury (remdesivir) is one of the key hospital-based antiviral treatments for COVID-19, designed to reduce viral replication and support recovery in selected patients. It is most effective when used early in disease progression under medical supervision.
