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Ciprofloxacin – Fluoroquinolone Antibiotic (Rx)

Ciprofloxacin is a broad-spectrum fluoroquinolone antibiotic used to treat a wide range of bacterial infections. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair, leading to bacterial cell death.

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It is commonly prescribed for infections such as urinary tract infections (UTIs), respiratory tract infections, gastrointestinal infections, skin infections, and certain sexually transmitted infections. Ciprofloxacin is particularly effective against many Gram-negative bacteria.

Nyckelfakta

• Active Ingredient: Ciprofloxacin
• Drug Class: Fluoroquinolone antibiotic
• Indikationer:
  • Urinary tract infections (UTIs)
  • Respiratory tract infections
  • Gastrointestinal infections (e.g., traveler’s diarrhea)
  • Skin and soft tissue infections
  • Bone and joint infections
• Mechanism of Action: Inhibits DNA gyrase & topoisomerase IV → bactericidal effect
• Spectrum: Broad-spectrum (strong Gram-negative coverage)
• Receptstatus: Receptbelagt läkemedel

Specifikationer

• Dosageformer:
  • Oral tablets
  • Oral suspension
  • Intravenous (IV) infusion
  • Ophthalmic and otic solutions
• Common Strengths (oral): 250 mg, 500 mg, 750 mg
• Administration: Oral or IV depending on severity
• Dosing Frequency: Usually twice daily (varies by infection)
• Onset of Action: Within hours of administration
• Half-Life: ~4 hours
• Metabolism: Partial hepatic metabolism
• Excretion: Primarily renal
• Förvaring: Rumstemperatur

Dosering och administrering

• Dose depends on type and severity of infection
• Typical adult oral dosing: 250–750 mg every 12 hours
• Complete the full prescribed course to prevent resistance
• Take with water; avoid taking simultaneously with antacids or calcium-rich products (they reduce absorption)

Kompatibilitet / Lämplig användning

• Adults with confirmed or suspected bacterial infections
• Patients requiring broad-spectrum antibiotic therapy
• Suitable for oral or IV treatment depending on severity
• Måste användas under medicinsk övervakning

Kontraindikationer

• Hypersensitivity to ciprofloxacin or other fluoroquinolones
• Use with tizanidine (contraindicated interaction)

Why Choose Ciprofloxacin?

Ciprofloxacin is a widely used broad-spectrum antibiotic with strong activity against Gram-negative bacteria. Its availability in multiple forms (oral and IV) and effectiveness in treating diverse infections make it a versatile option in clinical practice.