Beskrivning
Vyvanse (Lisdexamfetamine) – Long-Acting ADHD Stimulant (Rx, Controlled Substance)
Vyvanse (lisdexamfetamine) is a central nervous system stimulant used for the treatment of attention deficit hyperactivity disorder (ADHD) in children and adults, and binge eating disorder in adults.
It is a prodrug, meaning it is inactive until metabolized in the body into dextroamphetamine, which increases levels of dopamine and norepinephrine in the brain. This improves focus, attention, impulse control, and wakefulness.
Because it is converted gradually, Vyvanse provides a longer and smoother duration of action compared to some other stimulants.
Key Details
- Active Ingredient: Lisdexamfetamine dimesylate
- Converted to: Dextroamphetamine (active form)
- Drug Class: CNS stimulant (amphetamine prodrug)
- Indications:
- ADHD (children and adults)
- Binge eating disorder (adults)
- Mechanism of Action: Increases dopamine and norepinephrine activity via prodrug conversion
- Prescription Status: Strictly controlled prescription medicine
Specifikationer
- Dosage Forms: Oral capsules, chewable tablets
- Common Strengths: 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg
- Administration: Oral, once daily in the morning
- Onset of Action: ~1–2 hours
- Duration of Action: ~10–14 hours
- Half-Life: ~10–13 hours (active metabolite dependent)
- Metabolism: Converted in blood to dextroamphetamine
- Excretion: Renal
- Storage: Room temperature
Dosage & Administration
- Taken once daily in the morning
- Can be taken with or without food
- Dose is individually titrated by a healthcare provider
- Designed for all-day symptom coverage in ADHD
- Capsules may be opened and mixed with food (in some formulations)
Compatibility / Suitable Use
- Patients with ADHD requiring long-lasting symptom control
- Adults with binge eating disorder (approved indication in some regions)
- Suitable for individuals needing once-daily stimulant therapy
- Requires regular clinical monitoring (weight, heart rate, blood pressure)
Warnings & Precautions
- Risk of dependence, misuse, and abuse (controlled substance)
- May increase heart rate and blood pressure
- Can cause insomnia, anxiety, or irritability
- May suppress appetite and affect weight
- Avoid late-day dosing to prevent sleep disturbance
- Monitor for cardiovascular and psychiatric effects
Why Vyvanse Is Used
Vyvanse is widely prescribed for ADHD management due to its long duration and smoother effect profile, helping improve daily focus, attention control, and impulse regulation with once-daily dosing. It is also used in binge eating disorder treatment under specialist care.